How long until ziana works

The longer your skin cells are exposed to sunlight and air, the greater the effects of photoaging -- the process through which your skin starts to develop wrinkles, smile lines and other signs of aging. By stimulating skin cell turnover and exfoliating the layers of your skin that are exposed to direct sunlight, tretinoin plays a powerful role in slowing down and reversing the development of lines, wrinkles and discoloration.

In one study , researchers observed a clear improvement in skin quality after participants applied topical tretinoin 0. The study was 16 weeks long. In general, the cited studies of topical tretinoin for anti-aging showed results after approximately two to three months of daily use.

Long-term studies of tretinoin tend to show the most dramatic results, with people experiencing significant reductions in the appearance of fine wrinkling, coarse wrinkling, skin laxity and other signs of photoaging. In a study of people with photodamaged facial skin , half of the participants were given a cream containing tretinoin 0. After six months, participants given tretinoin showed significant improvements in fine wrinkling, coarse wrinkling, sallowness, looseness and hyperpigmentation.

These patients also reported a self-perceived improvement in an appraisal questionnaire. A study of long-term tretinoin treatment showed similar results. Participants given tretinoin 0. Interestingly, study participants given a cream with a lower amount of tretinoin 0.

List of Partners vendors. Ziana is a prescription acne treatment that's used to treat mild to severe acne. It's an alcohol-free, water-based gel that you apply directly to the skin, over the entire area where you're breaking out. Ziana is a combination acne treatment. This means it's actually a combination of two medications—the antibiotic clindamycin and the topical retinoid tretinoin. You probably know tretinoin by its more common brand name, Retin-A. It's only available by prescription, so you'll have to see a healthcare provider to get this medication.

You can't get it over-the-counter, and there's no OTC alternative. Since Ziana contains two active ingredients, it works to fight acne in two distinct ways. First, clindamycin is an antibiotic that's commonly used to treat acne. Clindamycin reduces the amount of Propionibacteria acnes found on the skin. These bacteria responsible, in part, for triggering inflamed acne breakouts. But, bacteria aren't the only acne trigger factors. Acne is also caused by blocked pores, and that's where the second active ingredient in Ziana, tretinoin, comes into play.

Tretinoin is better known by the name Retin-A. Tretinoin, a derivative of vitamin A, speeds up cell turnover rates.

This keeps pores unclogged and loosens existing comedones. Because of this, Ziana is effective against both inflammatory blemishes, such as pimples and papules and non-inflammatory blackheads and whiteheads. Ziana is applied just once per day, right after your nightly cleansing. You'll only need a pea-sized amount of the medication per application. Ziana can cause some side effects, but luckily they aren't too bothersome for most people. The side effects are typically minor and along the lines of:.

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Updated visitor guidelines. You are here Home » clindamycin and tretinoin topical. Top of the page. What is the most important information I should know about clindamycin and tretinoin topical? What is clindamycin and tretinoin topical? Clindamycin is an antibiotic. It fights bacteria in the body. What should I discuss with my health care provider before using clindamycin and tretinoin topical? This medicine should not be used on a child younger than 12 years old.

How should I use clindamycin and tretinoin topical? Wash your hands before and after applying this medication. Store at room temperature away from moisture, heat, and light. Do not freeze. What happens if I miss a dose? What happens if I overdose? Seek emergency medical attention or call the Poison Help line at What should I avoid while using clindamycin and tretinoin topical?